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Thymosin alpha 1 5mg/10mg

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Usage Thymosin alpha-1 is a 28-amino-acid peptide that modulates and supports immune function. Its synthetic version is known as thymalfasin. Key Clinical Uses Viral Infections: Used internationally as an adjunctive treatment for chronic hepatitis B and C, as well as in studies involving HIV/AIDS and severe acute infections. Cancer and Chemotherapy Support: Studied and utilized in specific settings to reduce chemotherapy-induced toxicity (such as lymphopenia) and support immune response alongside primary cancer treatments. Immune Deficiencies: Administered to help restore T-cell counts, enhance dendritic cell activity, and balance immune system responses. Mechanism of Action Acts as an agonist for Toll-like receptors (such as TLR2 and TLR9). Stimulates the maturation, differentiation, and proliferation of T-cells and other key immune cells. Modulates cytokine production to prevent extreme immune overreactions while bolstering defenses against pathogens.
HS Code 2937190099
Purity Not less than 99.00%
Application medicine
CAS No 62304-98-7
Storage Freezer
Properties Thymosin alpha-1 is a 28-amino-acid N-terminal acetylated peptide hormone naturally produced in the thymus gland, with its synthetic analogue known as thymalfasin. Structural and Chemical Properties Molecular Weight: Approximately 3,108 Da. Composition: A linear chain of 28 amino acid residues derived from the cleavage of prothymosin. Charge/Nature: Acidic molecule (designated in the alpha fraction) and heat-stable. Endogenous Levels: Typically ranges from 0.1 to 1.0 ng/mL in the human body. Biological and Immunological Mechanisms Immune Modulation: Acts as an immune system modulator rather than a simple stimulant, helping balance and restore immune responses. T-Cell Activity: Stimulates T-cell maturation, differentiation, and proliferation (including CD3+, CD4+, and CD8+ cells) and enhances thymic output. Receptor Agonist: Functions as a TLR-2 and TLR-9 agonist (and interacts with TLR4 pathways), activating myeloid and plasmacytoid dendritic cells as well as natural killer (NK) cells. Cytokine Regulation: Modulates and improves the production of key cytokines and interferons (such as IL-2, IL-3, IL-6, IL-10, IFN- , and TNF- ). Antioxidant and Anti-inflammatory Effects: Helps reduce excessive inflammation and supports intracellular glutathione levels.
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Thymosin alpha 1 5mg/10mg Price And Quantity

Minimum Order Quantity 10 Unit
Price 10.0 USD ($)/Unit

Thymosin alpha 1 5mg/10mg Product Specifications

Refractive Rate 1.563
Taste Odorless
Molecular Formula C129H215N33O55
Ingredients Thymosin alpha-1
Solubility Thymosin alpha 1 is slightly to readily soluble in water (typically achieving a solubility of 1 mg/mL or higher, depending on salt content and pH).
CAS No 62304-98-7
Storage Freezer
Properties Thymosin alpha-1 is a 28-amino-acid N-terminal acetylated peptide hormone naturally produced in the thymus gland, with its synthetic analogue known as thymalfasin. Structural and Chemical Properties Molecular Weight: Approximately 3,108 Da. Composition: A linear chain of 28 amino acid residues derived from the cleavage of prothymosin. Charge/Nature: Acidic molecule (designated in the alpha fraction) and heat-stable. Endogenous Levels: Typically ranges from 0.1 to 1.0 ng/mL in the human body. Biological and Immunological Mechanisms Immune Modulation: Acts as an immune system modulator rather than a simple stimulant, helping balance and restore immune responses. T-Cell Activity: Stimulates T-cell maturation, differentiation, and proliferation (including CD3+, CD4+, and CD8+ cells) and enhances thymic output. Receptor Agonist: Functions as a TLR-2 and TLR-9 agonist (and interacts with TLR4 pathways), activating myeloid and plasmacytoid dendritic cells as well as natural killer (NK) cells. Cytokine Regulation: Modulates and improves the production of key cytokines and interferons (such as IL-2, IL-3, IL-6, IL-10, IFN- , and TNF- ). Antioxidant and Anti-inflammatory Effects: Helps reduce excessive inflammation and supports intracellular glutathione levels.
Purity Not less than 99.00%
Application medicine
Usage Thymosin alpha-1 is a 28-amino-acid peptide that modulates and supports immune function. Its synthetic version is known as thymalfasin. Key Clinical Uses Viral Infections: Used internationally as an adjunctive treatment for chronic hepatitis B and C, as well as in studies involving HIV/AIDS and severe acute infections. Cancer and Chemotherapy Support: Studied and utilized in specific settings to reduce chemotherapy-induced toxicity (such as lymphopenia) and support immune response alongside primary cancer treatments. Immune Deficiencies: Administered to help restore T-cell counts, enhance dendritic cell activity, and balance immune system responses. Mechanism of Action Acts as an agonist for Toll-like receptors (such as TLR2 and TLR9). Stimulates the maturation, differentiation, and proliferation of T-cells and other key immune cells. Modulates cytokine production to prevent extreme immune overreactions while bolstering defenses against pathogens.
HS Code 2937190099
Shape other
EINECS No 1592732-453-0
Product Type Peptides
Appearance White powder
Physical Form Powder
Smell Other
Poisonous NO
Grade Research Grade
Shelf Life 18 Months
Density 1.360 0.06 Gram per cubic centimeter(g/cm3)

Thymosin alpha 1 5mg/10mg Trade Information

FOB Port Shenzhen or Guangzhou
Payment Terms Telegraphic Transfer (T/T), Western Union
Supply Ability 10000 Unit Per Week
Delivery Time 5 Days
Sample Available Yes
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Packaging Details 10 Vials per Box.
Main Export Market(s) Asia, Australia, North America, South America, Western Europe
Main Domestic Market All India
Certifications GMP, ISO9001

Product Description

Thymosin alpha 1 (T1) is a 28-amino-acid peptide naturally produced by the thymus gland. Its synthetic equivalent is known as thymalfasin (sold under the brand name ZADAXIN).

Key Characteristics

Structure & Origin: It is an N-terminal acetylated acidic peptide derived from the cleavage of the precursor protein prothymosin alpha.

Immune Modulator: Rather than aggressively pushing the immune system up or down, it acts as an immunomodulator (like a coach on the sidelines). It helps mature, balance, and stimulate T cells, dendritic cells, natural killer (NK) cells, and cytokine production via Toll-like receptors (TLR-2 and TLR-9).

History: It was first isolated from thymic tissue in 1977 by Allan Goldstein and colleagues.

Clinical Uses and Applications

Infections: Used or studied for chronic viral hepatitis (B and C), HIV, severe sepsis, and fungal or mold toxicity.

Oncology: Used as an adjunctive or co-therapy in certain cancers (such as melanoma and hepatocellular carcinoma) to help reduce chemotherapy toxicity and support immune function.

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