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Ruxolitinib Phosphate

3.6 USD ($)/Gram

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Product Details:

Melting Point 84-89
Molecular Formula C17H21N6O4P
EINECS No 1312995-182-4
Loss on Drying Not more than 0.5%
Taste Other
Solubility Ruxolitinib phosphate is soluble in water and some common organic solvents (such as DMSO or ethanol).
Storage Room Temperature
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Ruxolitinib Phosphate Price And Quantity

Price 3.6 USD ($)/Gram
Minimum Order Quantity 100 Gram

Ruxolitinib Phosphate Product Specifications

Medicine Name Ruxolitinib Phosphate
HS Code 2933599099
Ph Level 2.5 ~ 4.5
CAS No 1092939-17-7
Solubility Ruxolitinib phosphate is soluble in water and some common organic solvents (such as DMSO or ethanol).
Storage Room Temperature
Taste Other
Chemical Name (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
Smell Other
Molecular Weight 404.360201 Grams (g)
Molecular Formula C17H21N6O4P
Grade Medicine Grade
Shelf Life 36 Months
Type Other
Melting Point 84-89
Appearance White to almost white powder
Physical Form Powder
Usage Ruxolitinib has the following main effects: 1. MPN treatment: Ruxolitinib is widely used to treat MPN, including diseases such as chronic myeloid leukemia and primary myelofibrosis. It helps control the proliferation of abnormal bone marrow cells and relieves related symptoms. 2. Rheumatoid arthritis treatment: In some RA patients, ruxolitinib can relieve arthritis symptoms and improve quality of life, especially for those who are insensitive to or intolerant of traditional anti-rheumatic drugs. The drug has performed well in clinical trials, with significant efficacy and high safety. Ruxolitinib is a drug commonly used to treat myelofibrosis, polycythemia vera, and acute graft-versus-host disease refractory to corticosteroids. Its unique mechanism of action helps patients relieve symptoms and improve quality of life, bringing good news to many patients. 1. Therapeutic effect of myelofibrosis: Myelofibrosis is a bone marrow disease characterized by the proliferation of fibroblasts in the bone marrow, accompanied by fibrin deposition and destruction of hematopoietic tissue. Ruxolitinib phosphate can reduce the fibrotic reaction by inhibiting the activity of Janus kinase, thereby alleviating the symptoms of patients with myelofibrosis and delaying the progression of the disease. 2. Therapeutic effect of polycythemia vera: Polycythemia vera, also known as primary polycythemia vera, is a myeloproliferative disease in which the patient has too many red blood cells. Ruxolitinib can regulate the hematopoietic process by affecting the proliferation and differentiation pathways of stem cells, help control the number of red blood cells, and alleviate symptoms and complications. 3. Efficacy of corticosteroid-refractory acute graft-versus-host disease: In the treatment of corticosteroid-refractory acute graft-versus-host disease, ruxolitinib phosphate can inhibit the activity of T cells, reduce immune response, reduce the rejection reaction and complications after allogeneic hematopoietic stem cell transplantation, and improve the treatment effect.
Loss on Drying Not more than 0.5%
Purity(%) 98.0% ~ 102.0%
EINECS No 1312995-182-4

Ruxolitinib Phosphate Trade Information

FOB Port Shanghai, Beijing, Shenzhen or Dongguan
Payment Terms Paypal Letter of Credit at Sight (Sight L/C) Telegraphic Transfer (T/T) Western Union
Supply Ability 50000 Gram Per Month
Delivery Time 5 Days
Sample Available No
Sample Policy If order is confirmed we will reimburse the sample cost
Packaging Details 10g/Bag, 20g/Bag, 50g/Bag, 100g/Bag, 500g/Bag, 1kg/Bag or according to the specific requirements from customers.
Main Export Market(s) Australia North America South America Eastern Europe Western Europe

Product Description

Ruxolitinib Phosphate is the phosphate form of Ruxolitinib, which is a tyrosine kinase inhibitor and is mainly used clinically to treat myeloproliferative neoplasms such as chronic myeloid leukemia and myelofibrosis.

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