--+8615840669648

Our Products

APIs And Intermediates

Vitamins

Food Ingredients

Personal Care Chemicals

Pharmaceutical Excipients

China NAD+ 100mg/500mg/1000mg

5.0 USD ($)/Piece

Get a Price/Quote

Product Details:

Grade Research Grade
Properties 1. Core Components of Basic Chemistry and Physiology: NAD+ is composed of one nicotinamide nucleotide and one adenine nucleotide linked by a pyrophosphate bond. Redox State: NAD+ is in its oxidized form; when it accepts two electrons and a proton (hydrogen ion), it is converted to its reduced form (NADH). This interconversion of redox pairs is fundamental to energy production in organisms. Wide Distribution: As an endogenous substance, it naturally exists in every cell of the human body, mediating thousands of biochemical reactions. 2. Biological Functions: Energy Metabolism Hub: It participates in cellular respiration and is a key mediator in glycolysis, the tricarboxylic acid cycle (TCA), and the electron transport chain (respiratory chain), responsible for converting nutrients into cellular energy (ATP). DNA Repair: It is a substrate and activator of DNA repair enzymes (such as PARP), helping to repair DNA damage caused by ultraviolet radiation or oxidative stress. Activation of Longevity Proteins: As a key linker, NAD+ can activate longevity genes (Sirtuins, such as SIRT1-SIRT7), thereby regulating cellular senescence, inflammatory responses, and metabolic homeostasis. 3. Dynamic Consumption with Age: In a healthy state, the body's NAD+ concentration is in dynamic equilibrium. However, with age or prolonged exposure to high-pressure, unhealthy lifestyles, NAD+ synthesis decreases while consumption increases, leading to a significant decline in overall concentration. This is considered one of the important contributing factors to aging. 4. Clinical and Healthcare Applications for Anti-aging and Vitality Enhancement: Due to its ability to improve mitochondrial function and promote cell repair, it is often used to delay aging, alleviate mental fatigue, improve memory, and enhance physical strength.
Taste Other
Application Pharmaceutical
Ingredients NAD+
Shelf Life 24 Months
Molecular Formula C21H27N7O14P2
Click to View more

Request to Call Back Send Inquiry

Product Details
Product Description

China NAD+ 100mg/500mg/1000mg Price And Quantity

Minimum Order Quantity 10 Piece
Price 5.0 USD ($)/Piece

China NAD+ 100mg/500mg/1000mg Product Specifications

Smell Other
Grade Research Grade
Taste Other
Properties 1. Core Components of Basic Chemistry and Physiology: NAD+ is composed of one nicotinamide nucleotide and one adenine nucleotide linked by a pyrophosphate bond. Redox State: NAD+ is in its oxidized form; when it accepts two electrons and a proton (hydrogen ion), it is converted to its reduced form (NADH). This interconversion of redox pairs is fundamental to energy production in organisms. Wide Distribution: As an endogenous substance, it naturally exists in every cell of the human body, mediating thousands of biochemical reactions. 2. Biological Functions: Energy Metabolism Hub: It participates in cellular respiration and is a key mediator in glycolysis, the tricarboxylic acid cycle (TCA), and the electron transport chain (respiratory chain), responsible for converting nutrients into cellular energy (ATP). DNA Repair: It is a substrate and activator of DNA repair enzymes (such as PARP), helping to repair DNA damage caused by ultraviolet radiation or oxidative stress. Activation of Longevity Proteins: As a key linker, NAD+ can activate longevity genes (Sirtuins, such as SIRT1-SIRT7), thereby regulating cellular senescence, inflammatory responses, and metabolic homeostasis. 3. Dynamic Consumption with Age: In a healthy state, the body's NAD+ concentration is in dynamic equilibrium. However, with age or prolonged exposure to high-pressure, unhealthy lifestyles, NAD+ synthesis decreases while consumption increases, leading to a significant decline in overall concentration. This is considered one of the important contributing factors to aging. 4. Clinical and Healthcare Applications for Anti-aging and Vitality Enhancement: Due to its ability to improve mitochondrial function and promote cell repair, it is often used to delay aging, alleviate mental fatigue, improve memory, and enhance physical strength.
Shelf Life 24 Months
Appearance White powder
Application Pharmaceutical
Ingredients NAD+
Shape other
Physical Form Powder
Molecular Formula C21H27N7O14P2
Product Type Peptides
Storage Freezer
HS Code 2937190099
Poisonous NO
Solubility Soluble in water
EINECS No N/A
CAS No 53-84-9
Usage Boost Cellular Energy: As an "energy transmitter," it helps mitochondria convert food into ATP (acetylene trioxide), improving chronic fatigue and enhancing physical strength and energy. Initiate Cellular Repair: It activates "sirtuins" in the body, repairing damaged DNA and maintaining genome stability. Improve Brain Function: Providing ample energy to brain cells helps enhance memory, improve concentration, and alleviate brain fog. Regulate Biological Clock: It helps regulate the body's circadian rhythm, improving sleep quality. Anti-Aging and Skin Beautification: It promotes metabolism, combats oxidative stress, reduces skin blemishes, and improves skin elasticity and hydration.
Purity 99%

China NAD+ 100mg/500mg/1000mg Trade Information

FOB Port Shenzhen
Payment Terms Telegraphic Transfer (T/T), Western Union
Supply Ability 10000 Piece Per Week
Delivery Time 3 Days
Sample Available Yes
Sample Policy If order is confirmed we will reimburse the sample cost
Packaging Details 10 vials/box
Main Export Market(s) Asia, Western Europe, Australia, North America
Certifications GMP, ISO

Product Description

NAD+ (nicotinamide adenine dinucleotide) is a key coenzyme present in every cell of the human body, essential for cellular energy production and maintaining cellular health. As we age, the level of NAD+ in the body naturally declines, which is considered one of the core causes of aging and many age-related chronic diseases.

Tell us about your requirement

Price:

Quantity

Select Unit

50
100
200
250
500
1000+

Additional detail

Mobile number

Other Products in 'Peptide Preparations' category

KLOW 80mg Blend Price : 24.0 USD ($)/Piece Minimum Order Quantity : 10 Solubility : Soluble in water Usage : Klow Blend is a multipathway peptide formulation evaluated in experimental research for recovery, mitochondrial support, and longevity enhancement. Product Type : Peptides Storage : Freezer Appearance : Blue powder Physical Form : Powder Smell : Other Poisonous : NO Purity : 99.0% CAS No : N/A Application : Pharmaceutical Shelf Life : 24 Months Ingredients : BPC157, TB500, GHKCu, and KVP Grade : Research Grade Taste : Other Properties : KLOW Peptide Blend support tissue repair, inflammation control, and recovery in research models. Shape : other EINECS No : N/A HS Code : 2937190099 Molecular Weight : 1 Milligram (mg)

Send Inquiry

KPV China Price : 4.5 USD ($)/Piece Minimum Order Quantity : 10 Solubility : Soluble in water Usage : 1. Gut Health and Repair (Gastrointestinal Golden Partner) KPV's primary stage is the gut. When the gut is inflamed, the "portal" (PepT1 transporter) on intestinal cells increases significantly, allowing KPV to directly enter the inflamed cells and exert its effects. Relieving Enteritis: Commonly used in research and as an adjunct treatment for severe intestinal inflammation such as ulcerative colitis and Crohn's disease (IBD). Repairing Leaky Gut Syndrome: It strengthens the tight junctions of intestinal epithelial cells, repairs damaged intestinal mucosa, and resolves food intolerances and chronic allergies caused by "leaky gut." 2. Skin Repair and Antiinflammatory (Dermatology and Cosmetology) KPV can be absorbed through the skin, quickly reducing redness and stinging. Improving Chronic Skin Diseases: It has excellent soothing and improving effects on psoriasis, eczema, rosacea, and severe acne. Accelerating Wound Healing: It promotes skin cell regeneration, reduces wound infection, and prevents excessive scarring, resulting in smoother skin healing. 3. BroadSpectrum Antiinflammatory and Immune Balance Shutting Off Inflammation: It inhibits a core inflammatory factor called NF B in the body, thereby reducing the secretion of various harmful substances (such as proinflammatory cytokines) that cause redness, swelling, heat, and pain. Balancing Immunity: It doesn't brutally "suppress" the immune system, but rather "soothes" overexcited immune cells, making it beneficial for mast cell activation syndrome (MCAS) and certain autoimmune problems. 4. Antibacterial and Hair Growth (Emerging Research) Antibacterial Effect: Studies have found that it has a certain inhibitory effect on common pathogenic bacteria such as Staphylococcus aureus and Candida albicans. Preventing Hair Loss: In recent years, large skincare groups (such as L'Or al) have patented its use for hair growth. Research shows that KPV can stimulate hair growth by prolonging the hair's growth phase, while simultaneously improving scalp inflammation. Product Type : Peptides Storage : Freezer Appearance : White powder Physical Form : Powder Smell : Other Poisonous : NO Purity : 99% CAS No : 67727973 Application : Pharmaceutical Shelf Life : 24 Months Ingredients : KPV Grade : Research Grade Taste : Other Properties : Core Chemical and Physical Properties Small Molecular Structure: KPV has a molecular weight of approximately 342.43 g/mol. Its short molecular chain allows it to penetrate cell membranes more easily to exert its effects. High Water Solubility: It is highly soluble in water and buffered solutions, facilitating preparation and experimental use. Good Stability: Thanks to the presence of proline in its structure, KPV is more resistant to degradation by enzymes in vivo compared to ordinary longchain peptides, exhibiting greater stability. Core Biological Performance Characteristics 1. Potent Antiinflammatory Properties: KPV can directly enter cells and block the signaling pathways of proinflammatory factors (such as the NF B pathway). It can significantly reduce the production of inflammatory substances in the body (such as TNF and IL6), thereby rapidly relieving tissue redness and inflammation. 2. Unique "No Darkening" Property: While natural MSH hormones have antiinflammatory properties, they activate melanocortin receptors, leading to skin darkening. KPV does not activate these receptors; while maintaining its potent antiinflammatory function, it has no side effect of causing skin darkening. 3. Antibacterial and Wound Repair: Inhibits pathogens: Studies have confirmed its significant antibacterial effects against common pathogens such as Staphylococcus aureus and Candida albicans. Accelerates healing: It can accelerate the healing of skin and mucous membrane wounds, reduce scar formation, and bring better skin repair results. Shape : other Molecular Formula : C16H30N4O4 EINECS No : N/A HS Code : 2937190099

Send Inquiry

China LL-37 5mg Price : 12.0 USD ($)/Piece Minimum Order Quantity : 10 Solubility : Soluble in water Usage : 1. BroadSpectrum Antimicrobial (Natural Antibiotic) LL37 possesses a very strong direct bactericidal ability and is unlikely to induce bacterial resistance. Eliminating Bacteria: It has a strong killing effect on common bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Antiviral: It can destroy enveloped viruses (such as influenza virus and respiratory syncytial virus), preventing them from penetrating human cells. Inhibiting Fungi: It also has a significant inhibitory effect on fungi such as Candida albicans, which cause skin and mucous membrane infections. Disrupting Bacterial Biofilms: It can break down the "protective shell" (biofilm) formed by bacteria clump together, exposing and eliminating hidden bacteria. 2. Powerful Immunomodulatory Effects LL37 is not just a "killer," but also a balancer of the immune system. Recruiting Immune Cells (Sentinel Function): When an infection occurs in the body, LL37 releases signals to attract an "immune army" of neutrophils, macrophages, and other cells to the scene. Neutralizing Endotoxins: When bacteria die, they release toxic lipopolysaccharides (LPS/endotoxins), triggering severe systemic inflammatory responses (sepsis). LL37 can directly bind to and neutralize these toxins, preventing uncontrolled inflammation. 3. Promotes Wound Healing and Tissue Regeneration LL37 acts as an accelerator for wound repair when skin and mucous membranes are damaged. Promotes Skin Growth: It stimulates the division and migration of keratinocytes and epithelial cells, promoting rapid wound closure. Promotes Angiogenesis: It induces endothelial cells to form new microvessels, delivering oxygen and nutrients to damaged tissues, which is crucial for the healing of chronic ulcers such as diabetic foot. 4. Potential Antitumor and Metabolic Regulation Effects Bidirectional Tumor Regulation: In scientific research, LL37 has exhibited complex regulatory effects on various cancers. It can inhibit the growth of certain tumors (such as colon cancer) by inducing apoptosis, making it a current research hotspot in cancer immunotherapy. Product Type : Peptides Storage : Freezer Appearance : White powder Physical Form : Powder Smell : Other Poisonous : NO Purity : 99% CAS No : 154947667 Application : Pharmaceutical Shelf Life : 24 Months Ingredients : LL37 Grade : Research Grade Taste : Other Properties : 1. Physical Properties Appearance: The pure product is usually a white or offwhite lyophilized solid powder. Net Charge: Under normal bodily conditions (pH 7.4), it carries a strong positive charge of +6. This makes it highly attractive to negatively charged bacterial surfaces. Isoelectric Point (pI): Approximately 10.61. It is a strongly basic polypeptide. 2. Spatial Structure Characteristics Chameleonlike Structure (Structural Plasticity): In pure water: It has no fixed shape and a loose structure, mainly in a random coil state. In the presence of salt or in contact with cell membranes: It rapidly twists into a very stable helix structure. Perfect "Dual Nature" (Amphiphilicity): When it becomes an helix, it exhibits dual affinity: The hydrophilic side: One side is lined with positively charged amino acids (lysine, arginine), which readily bind to water and bacterial surfaces. Hydrophobic surface: The other side is lined with wateraverse amino acids (leucine, phenylalanine), which prefer to penetrate the lipid layer of bacterial cell membranes. 3. Environmental and Chemical Behavior Characteristics Concentrationdependent "aggregation" (oligomerization): At low concentrations (below 10 M), it prefers to work alone in solution (monomer form). At high concentrations or in saline environments, it aggregates in groups (forming dimers or tetramers). This aggregation behavior protects it from easy degradation by enzymes in the body. Salt sensitivity: The salt ion composition in solution alters its spatial shape. High concentrations of salt act as a shield, blocking its positive charge, thus slightly reducing its direct bactericidal rate, but not affecting its ability to call on immune cells. Protein resistance: Compared to other common peptides, LL37 exhibits strong resistance to degradation by human proteases when bound to cell membranes, allowing it to survive longer in inflamed wounds. Shape : other Molecular Formula : C205H340N60O53 EINECS No : N/A HS Code : 2937190099

Send Inquiry

Cathelicidin LL-37 (Human) Price : 8.6 USD ($)/Piece Minimum Order Quantity : 100 Solubility : Soluble in water or acidic buffer (such as 0.1% acetic acid) Usage : 1) New Drugs: Low expression of TLR2 and LL37 and low level of serum LL37 in children with atopic dermatitis (AD) suggest that AD has problems such as innate immunity and skin barrier function defects. Vitamin D may activate vitamin D receptors and promote LL37 expression through the TLR2 pathway, thereby protecting AD. Perhaps in the future, LL37related drugs can be designed to assist vitamin D in combating atopic dermatitis. Neonatal sepsis is mainly caused by infection. With the emergence of drugresistant bacteria, antibiotic selection has become increasingly difficult, so it is particularly important to improve one's own resistance. Studies have shown that vitamin D can increase the expression of the body's antimicrobial peptide LL37, thereby improving the body's ability to defend against infection and providing strong protection for antibiotic treatment. This will provide ideas for designing drugs that replace antibiotics. 2) Animal Feed Additives: LL37 has a broad antibacterial spectrum and high antibacterial activity, bacteria are not easy to develop drug resistance, it can also neutralize endotoxins and can be regarded as a new alternative to antibiotics. Therefore, choosing a suitable expression template to express LL37 analogs will promote the production of animal feed additives with high antibacterial efficiency and high nutrition, making it have certain economic benefits. 3) Preservatives: LL37 and CP1 are produced on a large scale through genetic engineering, they have strong antibacterial activity, small relative molecular mass, high antibacterial activity when heated at 121 for 30 minutes, good water solubility, safe and nontoxic, and not easy to develop drug resistance. Adding an appropriate amount of antimicrobial peptides to milk has a certain preservation effect on storage. Product Type : Lyophilized Powder Storage : Freezer Appearance : White powder Physical Form : Powder Smell : Other Poisonous : NO Purity : 99.0% CAS No : 154947667 Application : Pharmaceutical Shelf Life : 24 Months Ingredients : LL37 Grade : Reagent Grade Taste : Other Properties : 1) Antimicrobial: As an important member of the natural immune system, LL37 has strong antimicrobial activity both in vivo and in vitro, including Grampositive bacteria (such as Staphylococcus aureus, Streptococcus, etc.), Gramnegative bacteria (such as Salmonella, Escherichia coli, etc.), fungi and viruses. Moreover, LL37 also has a certain selective killing effect on some fungi, viruses, tumor cells and protozoa. 2) Regulate the Release of Immune and Inflammatory Mediators: LL37 can cause immune cell differentiation and chemotaxis, induce cell differentiation, cytokine release, neutralize endotoxins and antitumor, etc., and enhance the body's ability to resist harmful microorganisms. Advantages: Compared with traditional antibiotics, Antimicrobial Peptide LL37 human can kill pathogens, is not easy to produce drug resistance, and is not easy to produce immune rejection reactions. It is an important effector molecule of the natural immune system. Shape : other Molecular Formula : C205H340N60O53 EINECS No : 2115199 Molecular Weight : 4493.74 Grams (g)

Send Inquiry

SEND INQUIRY CALL ME FREE

Quick Inquiry

Quick Links

Contact Details

DALIAN HANDOM CHEMICALS CO.,LTD.

RM702, Unit 1, Building 21, Liuhe Road, Ganjingzi Dist,Dalian - 116091, Liaoning, China

Phone :--+8615840669648

Mr John Wang (Manager)

Mobile :+8615840669648

Send Inquiry

E-mail us : export@handom-chem.com