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Bremelanotide (PT-141)

5.4 USD ($)/Piece

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Product Details:

Purity Not less than 99%
Product Type Lyophilized Powder
Physical Form Powder
Smell Other
Appearance White powder
Molecular Formula C50H68N14O10
Solubility Slightly soluble in water, DMSO and methanol, requires ultrasound-assisted dissolution.
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Product Description

Bremelanotide (PT-141) Price And Quantity

Minimum Order Quantity 10 Piece
Price 5.4 USD ($)/Piece

Bremelanotide (PT-141) Product Specifications

Shelf Life 24 Months
Solubility Slightly soluble in water, DMSO and methanol, requires ultrasound-assisted dissolution.
Application medicine
CAS No 1607799-13-2
Storage Freezer
Physical Form Powder
Smell Other
Molecular Formula C50H68N14O10
Appearance White powder
Purity Not less than 99%
Product Type Lyophilized Powder
Poisonous NO
Taste Other
Ingredients Bremelanotide
Properties PT-141 (also known as bremelanotide) is a melanocortin receptor agonist that primarily acts on melanocortin receptor type 4 (MC4R), which is present in the central nervous system (CNS) and regulates functions such as appetite, sexual behavior, and skin pigmentation. Chemical Properties: PT-141 is a cyclic peptide that is highly soluble in water and has a pKa value of 7.3. Its molecular formula is C50H68N14O10 and its molecular weight is 1025.163. PT-141 is a white powder with a melting point of approximately 150 C and a density of 1.4 0.1 g/cm3. Biological Activity: PT-141 is an analog of -melanocyte stimulating hormone ( -MSH) that activates mPOA in the central nervous system and other hypothalamic and limbic areas of the brain involved in sexual behavior. It is primarily used to study Hypoactive Sexual Desire Disorder(HSDD). In addition, PT-141 also has the effect of stimulating the production and secretion of melanin.
Molecular Weight 1025.16 Grams (g)
Grade Reagent Grade
Usage 1) Indications: PT-141 is mainly used to treat female hypoactive sexual desire disorder (HSDD), especially premenopausal women. It was approved by the US FDA on June 21st, 2019, with the trade name Vyleesi , and the dosage form is subcutaneous injection. Efficacy Characteristics: Clinical trials show that its efficacy peaks about 4 hours after injection, can quickly stimulate sexual desire, and is non-addictive.

Bremelanotide (PT-141) Trade Information

FOB Port Shenzhen, Dongguan, Shanghai or Beijing
Payment Terms Paypal, Telegraphic Transfer (T/T), Western Union
Supply Ability 5000 Piece Per Week
Delivery Time 3 Days
Sample Available No
Sample Policy If order is confirmed we will reimburse the sample cost
Packaging Details 10 Vials per Box (10mg/vial*10vials).
Main Export Market(s) Central America, North America, South America, Eastern Europe, Western Europe, Australia

Product Description

PT-141 (Bremelanotide) is a synthetic peptide drug that acts as an analog of -melanocyte stimulating hormone (-MSH) by activating melanocortin receptors (MCR).

PT-141 is mainly used to study and treat female sexual dysfunction, especially hypoactive sexual desire disorder.

In clinical trials, PT-141 showed significant effects on premenopausal women with hypoactive sexual desire disorder and helped them maintain normal sexual desire.

How Does Bremelanotide (PT-141) Work?

PT-141 is a cyclic peptide that targets melanocortin receptor type 4 (MC4R) in the brain, influencing areas linked to sexual desire and behavior. It quickly stimulates libido through central mechanisms, unlike other treatments that act directly on blood flow.

Clinical Applications and Benefits

PT-141 is principally administered for the management of female HSDD, providing a rapid onset for increased sexual desire. Its action peaks at roughly four hours post-injection and its non-addictive profile contributes to its safety as a therapeutic agent.

Proper Storage and Handling Guidelines

To maintain optimal potency, store PT-141 in a freezer. The shelf life extends up to 24 months under these conditions. Dissolution requires assistance, such as ultrasound, due to its limited solubility in water, DMSO, and methanol.

FAQs of Bremelanotide (PT-141):

Q: How should Bremelanotide (PT-141) be stored for maximum shelf life?

A: PT-141 should be securely stored in a freezer, where it can retain its efficacy for up to 24 months. Avoid exposure to heat or moisture to preserve its reagent-grade purity and stability.

Q: What is the approved usage of PT-141?

A: PT-141, marketed as Vyleesi, is approved for subcutaneous injection to treat hypoactive sexual desire disorder (HSDD) in premenopausal women, with peak effectiveness occurring about four hours post-administration.

Q: Where does PT-141 exert its effects in the body?

A: PT-141 primarily acts on melanocortin receptor type 4 (MC4R) within the central nervous system, particularly in regions responsible for sexual desire, appetite, and skin pigmentation.

Q: What is the typical process for preparing PT-141 for injection?

A: Due to its slight solubility, PT-141 powder requires dissolution in water, DMSO, or methanol, ideally using ultrasound to assist. Once dissolved, it is administered as a subcutaneous injection under medical guidance.

Q: What are the main benefits of using PT-141 compared to other treatments?

A: PT-141s central action allows rapid stimulation of sexual desire without causing dependency. Its effectiveness peaks quickly and it is particularly suited for premenopausal women managing HSDD.

Q: Is PT-141 considered poisonous or addictive?

A: No, PT-141 is classified as non-poisonous and clinical research indicates it does not promote addiction, contributing to its favorable safety profile for medical use.

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