CJC-1295 without DAC 2mg/5mg/10mg

BPC-157 China Price : 4.0 USD ($)/Piece Minimum Order Quantity : 10 CAS No : 137525510 Taste : Odorless Usage : BPC157 (Body Protection Compound157) is an experimental synthetic peptide derived from a protein found in human gastric juice. Smell : Other Shape : other Ingredients : BPC157 Physical Form : Powder Solubility : BPC157 is highly soluble in water, with a solubility of 100 mg/mL. Purity : Not less than 99.00% Appearance : White powder Grade : Research Grade Poisonous : NO Storage : Freezer Molecular Formula : C62H98N16O22 Properties : BPC157 (Body Protection Compound157) is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. Chemical and Physical Properties Amino Acid Sequence: GlyGluProProProGlyLysProAlaAspAspAlaGlyLeuVal (15 amino acids) Molecular Formula / Weight: C H N O / 1,419.56 g/mol Solubility & Stability: Freely soluble in water at normal pH. Uniquely stable in human gastric juice and acidic environments (resisting degradation for over 24 hours ex vivo). Pharmacokinetics: Rapid elimination with a plasma halflife under 30 minutes in animal models. Demonstrates variable bioavailability depending on the administration route (e.g., ~14 19% intramuscular in rats; ~45 51% in dogs). Biological and Pharmacological Mechanisms Angiogenesis: Stimulates vascular endothelial growth factor receptor 2 (VEGFR2) and promotes new blood vessel formation. Nitric Oxide (NO) System: Interacts with the Larginine/NO pathway, stimulating endothelial nitric oxide synthase (eNOS) activity. Growth Factor Signaling: Increases growth hormone receptor (GHR) expression in tendon fibroblasts and amplifies focal adhesion kinase (FAK) paxillin signaling pathways. Cytoprotection: Acts as a stabilizer of the endothelium and counteracts toxic or inflammatory insults (such as NSAID or alcoholinduced lesions) in the gastrointestinal tract. Application : Pharmaceutical Shelf Life : 18 Months Product Type : Peptides HS Code : 2937190099 EINECS No : 2115199 Refractive Rate : 1.575~1.576 Density : 1.366 0.06 Gram per cubic centimeter(g/cm3) Ph Level : 3.36 0.10

Thymosin alpha 1 China Price : 10.0 USD ($)/Piece Minimum Order Quantity : 10 CAS No : 62304987 Taste : Odorless Usage : Thymosin alpha1 (a synthetic analog often referred to as thymalfasin; brand names include Zadaxin) is a 28aminoacid peptide primarily used for immunomodulation and enhancing the body s resistance. Primary Uses and Clinical Applications Chronic Viral Infections: Approved in over 35 countries for the treatment of chronic hepatitis B and chronic hepatitis C, it aids in viral clearance and the regulation of immune responses. Adjunctive Cancer Therapy: Used as an adjuvant to chemotherapy or immunotherapy to mitigate chemotherapyinduced immunosuppression and improve patient outcomes (e.g., in nonsmall cell lung cancer). Severe Infections and Sepsis: Employed in cases of sepsis, HIV/AIDS, and certain severe infections (such as lymphocytopenia associated with severe COVID19) to help restore Tcell counts. Immune Deficiency and AntiAging Support: In some countries, it is used in clinical or antiaging/wellness settings to address reduced resistance resulting from aging or compromised immune function. Administration and Typical Dosing (Reference Regimen) Route of Administration: Typically administered via subcutaneous (SubQ) injection; this can be performed at home under a physician s guidance or in a clinical setting. Common Dosage and Frequency: The standard adult subcutaneous dose is approximately 1.5 mg, typically administered once every 3 days, or 2 3 times per week. For acute or shortterm viral infections, the treatment course is generally around 2 weeks; for complex immunomodulatory needs such as chronic hepatitis, HIV, or cancer the treatment course often lasts 3 months or longer. Smell : Other Shape : other Ingredients : Thymosin alpha 1 Physical Form : Powder Solubility : It is slightly soluble or soluble in water, readily soluble in acidic peptidesolubilizing agents such as trifluoroacetic acid (TFA), and insoluble in common organic solvents such as acetonitrile and diethyl ether. Purity : 99.00% Appearance : White powder Grade : Research Grade Poisonous : NO Storage : Freezer Molecular Formula : C129H215N33O55 Properties : Thymosin alpha 1 (often referred to as Thymalfasin in its synthetic analog form) is a 28aminoacid peptide derived from the thymus gland. It possesses properties such as bidirectional immunomodulation and antiinflammatory activity. 1. Basic Physicochemical Properties Molecular Structure: A small, naturally occurring peptide composed of 28 amino acid residues. Synthetic Form: The Thymalfasin used clinically is chemically and spatially identical to the naturally occurring human thymosin alpha 1. Route of Administration: Typically administered via subcutaneous injection. 2. Pharmacological and Immunomodulatory Properties Tcell Regulation: Stimulates peripheral blood lymphocytes, promoting the maturation and proliferation of T lymphocytes. Cytokine Induction: Enhances the secretion of lymphokines such as interferonalpha (IFN ), interferongamma (IFN ), interleukin2 (IL2), and interleukin3 (IL3) by T cells, and increases the expression of lymphokine receptors on cell surfaces. Innate Immune Activation: Acts as an agonist for Tolllike receptors 2 and 9 (TLR2 and TLR9), helping to regulate immune homeostasis. NK Cell Activation: Promotes the recruitment of NK cell precursors and enhances their cytotoxicity. Antiinflammatory and Antioxidant Effects: Helps mitigate excessive inflammatory responses and reduces damage caused by oxidative stress. 3. Clinical Applications Chronic Viral Infections: Frequently used in the treatment of conditions such as chronic hepatitis B and AIDS. Immunodeficiency and Adjuvant Therapy: Employed for congenital immunodeficiencies, sepsis, and as an adjunct in cancer treatment; also serves as an immuneenhancing adjuvant for vaccines. Mitigation of Chemotherapy/Radiotherapy Toxicity: Can improve outcomes for patients with compromised immune function and alleviate the immunosuppression induced by certain medical treatments. Application : Pharmaceutical Shelf Life : 18 Months Product Type : Peptides HS Code : 2937190099 EINECS No : 15927324530 Refractive Rate : 1.563 Density : 1.360 0.06 Gram per cubic centimeter(g/cm3) Ph Level : 4.2

KPV China Price : 4.5 USD ($)/Piece Minimum Order Quantity : 10 CAS No : 67727973 Taste : Other Usage : 1. Gut Health and Repair (Gastrointestinal Golden Partner) KPV's primary stage is the gut. When the gut is inflamed, the "portal" (PepT1 transporter) on intestinal cells increases significantly, allowing KPV to directly enter the inflamed cells and exert its effects. Relieving Enteritis: Commonly used in research and as an adjunct treatment for severe intestinal inflammation such as ulcerative colitis and Crohn's disease (IBD). Repairing Leaky Gut Syndrome: It strengthens the tight junctions of intestinal epithelial cells, repairs damaged intestinal mucosa, and resolves food intolerances and chronic allergies caused by "leaky gut." 2. Skin Repair and Antiinflammatory (Dermatology and Cosmetology) KPV can be absorbed through the skin, quickly reducing redness and stinging. Improving Chronic Skin Diseases: It has excellent soothing and improving effects on psoriasis, eczema, rosacea, and severe acne. Accelerating Wound Healing: It promotes skin cell regeneration, reduces wound infection, and prevents excessive scarring, resulting in smoother skin healing. 3. BroadSpectrum Antiinflammatory and Immune Balance Shutting Off Inflammation: It inhibits a core inflammatory factor called NF B in the body, thereby reducing the secretion of various harmful substances (such as proinflammatory cytokines) that cause redness, swelling, heat, and pain. Balancing Immunity: It doesn't brutally "suppress" the immune system, but rather "soothes" overexcited immune cells, making it beneficial for mast cell activation syndrome (MCAS) and certain autoimmune problems. 4. Antibacterial and Hair Growth (Emerging Research) Antibacterial Effect: Studies have found that it has a certain inhibitory effect on common pathogenic bacteria such as Staphylococcus aureus and Candida albicans. Preventing Hair Loss: In recent years, large skincare groups (such as L'Or al) have patented its use for hair growth. Research shows that KPV can stimulate hair growth by prolonging the hair's growth phase, while simultaneously improving scalp inflammation. Smell : Other Shape : other Ingredients : KPV Physical Form : Powder Solubility : Soluble in water Purity : 99% Appearance : White powder Grade : Research Grade Poisonous : NO Storage : Freezer Molecular Formula : C16H30N4O4 Properties : Core Chemical and Physical Properties Small Molecular Structure: KPV has a molecular weight of approximately 342.43 g/mol. Its short molecular chain allows it to penetrate cell membranes more easily to exert its effects. High Water Solubility: It is highly soluble in water and buffered solutions, facilitating preparation and experimental use. Good Stability: Thanks to the presence of proline in its structure, KPV is more resistant to degradation by enzymes in vivo compared to ordinary longchain peptides, exhibiting greater stability. Core Biological Performance Characteristics 1. Potent Antiinflammatory Properties: KPV can directly enter cells and block the signaling pathways of proinflammatory factors (such as the NF B pathway). It can significantly reduce the production of inflammatory substances in the body (such as TNF and IL6), thereby rapidly relieving tissue redness and inflammation. 2. Unique "No Darkening" Property: While natural MSH hormones have antiinflammatory properties, they activate melanocortin receptors, leading to skin darkening. KPV does not activate these receptors; while maintaining its potent antiinflammatory function, it has no side effect of causing skin darkening. 3. Antibacterial and Wound Repair: Inhibits pathogens: Studies have confirmed its significant antibacterial effects against common pathogens such as Staphylococcus aureus and Candida albicans. Accelerates healing: It can accelerate the healing of skin and mucous membrane wounds, reduce scar formation, and bring better skin repair results. Application : Pharmaceutical Shelf Life : 24 Months Product Type : Peptides HS Code : 2937190099 EINECS No : N/A

LL-37 Chemical Price : 12.0 USD ($)/Piece Minimum Order Quantity : 10 CAS No : 154947667 Taste : Other Usage : 1. Research on Superbugs and DrugResistant Bacteria (New Antibiotic Development) With the increasing severity of antibiotic resistance (AMR) problems, LL37 has become an ideal template for researching new antibacterial drugs. Disrupting Resistant Biofilms: It not only directly kills free bacteria but also disrupts the "bacterial biofilm" formed by Staphylococcus aureus or Pseudomonas aeruginosa. This is an area where many traditional antibiotics are ineffective. Enhancing Drug Efficacy through Combination Therapy: In scientific experiments, researchers often combine low doses of LL37 with traditional antibiotics, which can significantly improve the antibiotic's effectiveness against superbugs. 2. Chronic Wound Healing and Skin Repair (Clinical Drug Development) LL37 has shown significant effects in promoting tissue regeneration and has made rapid progress in clinical translation. Treatment of Lower Extremity Venous Ulcers: LL37related drugs, supported by institutions such as the Karolinska Institute in Sweden, have entered Phase II clinical trials internationally for the treatment of chronic ulcers caused by varicose veins. Promoting Angiogenesis and Epithelial Growth: It stimulates the growth of vascular endothelial cells, attracts immune cells to wounds, and enables chronic wounds lacking this component (such as diabetic foot) to resume granulation and healing. 3. Gastrointestinal Tract and Mucosal Immune Barrier Research LL37 is widely present in the human gastrointestinal mucosa. Scientists are using it to study the pathological mechanisms and treatment strategies of inflammatory bowel disease (IBD), gut microbiota dysbiosis, and gastric ulcers. Eye and Respiratory Protection:** Research focuses on how it protects the cornea from infection and its protective role in acute lung injury or respiratory infections. 4. Disease Diagnostic Markers and Targeted Therapy (Psoriasis, etc.) Because the amount of LL37 is directly related to the level of inflammation in the body, it is also used as a target for medical diagnostics and targeted research. Autoimmune Disease Target: In the skin lesions of patients with psoriasis and rosacea, the expression level of LL37 is often abnormally elevated and exacerbates inflammation. Therefore, developing drugs that "inhibit or antagonize LL37" has become a new approach to treating these skin diseases. Smell : Other Shape : other Ingredients : LL37 Physical Form : Powder Solubility : Soluble in water Purity : 99% Appearance : White powder Grade : Research Grade Poisonous : NO Storage : Freezer Molecular Formula : C205H340N60O53 Properties : 1. Physical Properties Appearance: The pure product is usually a white or offwhite lyophilized solid powder. Net Charge: Under normal bodily conditions (pH 7.4), it carries a strong positive charge of +6. This makes it highly attractive to negatively charged bacterial surfaces. Isoelectric Point (pI): Approximately 10.61. It is a strongly basic polypeptide. 2. Spatial Structure Characteristics Chameleonlike Structure (Structural Plasticity): In pure water: It has no fixed shape and a loose structure, mainly in a random coil state. In the presence of salt or in contact with cell membranes: It rapidly twists into a very stable helix structure. Perfect "Dual Nature" (Amphiphilicity): When it becomes an helix, it exhibits dual affinity: The hydrophilic side: One side is lined with positively charged amino acids (lysine, arginine), which readily bind to water and bacterial surfaces. Hydrophobic surface: The other side is lined with wateraverse amino acids (leucine, phenylalanine), which prefer to penetrate the lipid layer of bacterial cell membranes. 3. Environmental and Chemical Behavior Characteristics Concentrationdependent "aggregation" (oligomerization): At low concentrations (below 10 M), it prefers to work alone in solution (monomer form). At high concentrations or in saline environments, it aggregates in groups (forming dimers or tetramers). This aggregation behavior protects it from easy degradation by enzymes in the body. Salt sensitivity: The salt ion composition in solution alters its spatial shape. High concentrations of salt act as a shield, blocking its positive charge, thus slightly reducing its direct bactericidal rate, but not affecting its ability to call on immune cells. Protein resistance: Compared to other common peptides, LL37 exhibits strong resistance to degradation by human proteases when bound to cell membranes, allowing it to survive longer in inflamed wounds. Application : Pharmaceutical Shelf Life : 24 Months Product Type : Peptides HS Code : 2937190099 EINECS No : N/A