MOTS-c China

TB500 (Thymosin B4 Acetate) Price : 5.0 USD ($)/Piece Minimum Order Quantity : 100 Physical Form : Powder Properties : 1. Promote Cell Migration and Repair: Accelerate the repair of damaged tissues (such as muscles, tendons, and joints) by regulating actin (cytoskeletal protein). Stimulate angiogenesis, improve local blood circulation, and promote nutrient supply. 2. Antiinflammatory Effect: Reduce the release of inflammatory factors and relieve inflammatory reactions after tissue damage. 3. Enhance Flexibility and Adaptability: May improve the elasticity of muscles and connective tissues and reduce scar formation. Usage : 1) Sports Medicine: Athletes or fitness enthusiasts use it to accelerate the recovery of muscle strains and ligament tears. 2) Chronic Injuries: Auxiliary treatment of arthritis and tendinitis. 3) Skin Repair: Promote the healing of burns or surgical wounds (experimental stage). Shelf Life : 24 Months Grade : Reagent Grade Solubility : Soluble in water Purity : Not less than 99% CAS No : 77591334 Ingredients : Thymosin Beta 4 Acetate Poisonous : NO Appearance : White powder Taste : Other Smell : Other Product Type : Lyophilized Powder Application : Pharmaceutical Storage : Freezer Molecular Formula : C212H350N56O78S Molecular Weight : 4963.4408 EINECS No : 15927324530

Semax 5mg 10mg 30mg Price : 3.8 USD ($)/Piece Minimum Order Quantity : 10 Physical Form : Powder Properties : Semax is a synthetic neuroprotective peptide primarily used in stroke research and central nervous system function regulation. As an analog of the adrenocorticotropic hormone (ACTH) fragment, it crosses the bloodbrain barrier through a unique mechanism, promoting nerve regeneration and repair. In experimental models, it has shown potential to improve cerebral blood flow and regulate neurotransmitter activity; however, its clinical application requires further validation. I. Structure and Bioactivity: Semax is a synthetic analog of the ACTH (410) fragment. Its chemical structure removes the hormonal activity while retaining its neuroregulatory function. Its derivative, Semax acetate (CAS 2828433334), has become the primary form in research due to its enhanced stability and improved bioavailability. This modification allows it to rapidly cross the bloodbrain barrier after intranasal administration, with a single dose lasting up to 24 hours, making it suitable for acute neurological injury scenarios. II. Mechanism of Action and Neuroprotective Effects: Semax exerts its effects through a dual pathway: Promoting the expression of neurotrophic factors: Upregulating the levels of BDNF and its receptor TrkB in the hippocampus, directly supporting neuronal survival and synaptic plasticity, and accelerating neural circuit reconstruction after injury; Regulating the neurotransmitter system: Activating the serotonin and dopamine pathways, improving mood and cognitive function. Experiments show that it can counteract cognitive impairment caused by chronic stress, while enhancing Dphenylpropanolinduced motor activity, suggesting that it has a bidirectional regulatory capacity on neural excitability. Usage : Semax possesses immunomodulatory, nootropic, and neuroprotective activities. Semax can be used in research on central nervous system diseases such as Alzheimer's disease and cerebral ischemia. Shelf Life : 18 Months Grade : Research Grade Solubility : Soluble in water Purity : 99.0% CAS No : 80714610 Ingredients : Semax Poisonous : NO Appearance : White powder Taste : Other Smell : Other Product Type : Peptides Application : Pharmaceutical Storage : Freezer Molecular Formula : C37H51N9O10S Molecular Weight : 813.92 Milligram (mg) EINECS No : N/A Shape : other HS Code : 2937190099

Tesamorelin 2mg 5mg 10mg 20mg Price : 5.8 USD ($)/Piece Minimum Order Quantity : 10 Physical Form : Powder Properties : Tesamorelin is a synthetic growth hormonereleasing hormone analogue primarily used to reduce visceral fat accumulation (lipodystrophy) in HIVinfected individuals. Its core characteristics can be summarized as follows: 1) Pharmacological Properties: Mechanism of Action: It is a growth hormonereleasing factor (GRF) analogue that binds to and activates GRF receptors in the pituitary gland, stimulating the pituitary to secrete endogenous growth hormone (GH) in a pulsatile manner. Subsequently, growth hormone stimulates the liver to produce insulinlike growth factor 1 (IGF1), which mediates most of the biological effects, including reducing visceral fat and regulating metabolism. Hepatic Effects: In clinical trials, tesamorelin did not cause elevated serum transaminases or significant liver damage; on the contrary, it was even associated with lowering existing ALT levels, potentially improving nonalcoholic fatty liver disease. 2) Pharmacokinetic Properties: Absorption and Bioavailability: Administered subcutaneously, the amount absorbed into systemic circulation is very limited, with an absolute bioavailability of less than 4%. Its pharmacokinetic characteristics are similar in HIVinfected individuals and healthy subjects, and are not significantly affected by factors such as age, body size, or race. Distribution and elimination: It has a large volume of distribution, averaging 200 liters; the elimination halflife is very short, approximately 826 minutes in healthy subjects and approximately 38 minutes in HIVinfected individuals. Metabolism and excretion: There are currently no formal human metabolic studies. 3) Clinical Characteristics: Primary indication: For reducing excess abdominal fat in patients with HIVrelated lipodystrophy. It is important to emphasize that this is not a general medication for weight loss. Efficacy: Clinical studies have shown that daily subcutaneous injection of 2 mg for 26 weeks significantly reduces visceral adipose tissue (VAT) (average reduction of approximately 1418%), with no adverse effects on subcutaneous fat in the extremities. It also lowers triglyceride levels. Administration: Once daily, subcutaneous injection. Dosage varies depending on the drug strength. For example, the recommended dose for the 1 mg/vial strength is 2 mg daily; the recommended dose for the 2 mg/vial strength (Egrifta SV) is 1.4 mg daily. 4) Safety Characteristics: Common Side Effects: Primarily include injection site reactions (such as redness, swelling, pain, and itching), arthralgia, muscle pain, and limb pain. Side Effects to Watch Out For: May cause elevated blood sugar (increased risk of glucose intolerance or type 2 diabetes), therefore, caution should be exercised in diabetic patients. In addition, fluid retention (manifested as arthralgia, carpal tunnel syndrome), allergic reactions (such as rash, shortness of breath), and antibody production may occur (occurring in approximately 50% of patients, but usually does not affect efficacy). Contraindications: Contraindicated in patients with hypersensitivity to any of the drug components, those with an active or previous history of malignancy, and patients with pituitaryrelated diseases (such as pituitary tumors). Contraindicated in pregnant women as it may harm the fetus. Drug Interactions: Concomitant use with corticosteroids (such as prednisone) may reduce the efficacy of the latter. No clinically significant interactions were observed when used in combination with simvastatin or ritonavir. It has minimal effect on the hepatic CYP3A enzyme system. 5) Chemical Properties: Chemical Nature: It is a polypeptide composed of 44 amino acids and is a synthetic analog of human natural growth hormonereleasing hormone (GHRH). Its chemical structure is C221H366N72O67S. Structural Modification: The Nterminus of its molecule has been modified (by adding a trans3hexenoyl group) to increase its stability and prolong its duration of action. Appearance: Usually a sterile, preservativefree lyophilized powder, which must be dissolved in the matching diluent before use. Usage : The primary use of Tesamorelin is to treat lipid dystrophism in HIVinfected individuals, specifically by reducing excess visceral fat around the liver. Main Uses and Efficacy: This drug works by mimicking the body natural growth hormonereleasing hormone, stimulating the pituitary gland to secrete growth hormone, thereby specifically regulating lipid metabolism. Multiple clinical studies have confirmed its effectiveness in the following areas: 1) Reducing Visceral Fat: Significantly reduces abdominal visceral fat accumulation (average reduction of approximately 14%18%) and shrinks waist circumference. 2) Improving Liver Fat: Significantly reduces liver fat content, particularly beneficial for patients with HIV and metabolicrelated fatty liver disease. 3) Optimizing Body Composition: While reducing trunk fat, it increases lean body mass (muscle mass) with minimal impact on subcutaneous fat. Shelf Life : 18 Months Grade : Research Grade Solubility : Soluble in water Purity : 99.0% CAS No : 218949485 Ingredients : Tesamorelin Poisonous : NO Appearance : White powder Taste : Other Smell : Other Product Type : Peptides Application : Pharmaceutical Storage : Freezer Molecular Formula : C221H366N72O67S Molecular Weight : 5135.86 Milligram (mg) EINECS No : 6038092 Shape : other HS Code : 2937190099

GLOW 70mg Blend Price : 22.0 USD ($)/Piece Minimum Order Quantity : 10 Physical Form : Powder Properties : GLOW 70mg blend is a formula that blends three peptides to work synergistically on multiple levels to promote the body's recovery and regeneration. Its key feature is that it is not limited to skin care, but focuses more on the systemic repair of tissues such as muscles, tendons, and the intestines. Usage : 1) Skin and Tissue Repair: Improves skin density and elasticity by stimulating collagen synthesis and accelerates wound healing. 2) Sports Recovery: Accelerates the repair of sports injuries such as tendons, ligaments, and muscles; often studied for treating chronic or old injuries. 3) Antiinflammatory and Gut Health: Regulates inflammatory responses, while the BPC157 component helps support gut health. Shelf Life : 18 Months Grade : Research Grade Solubility : Soluble in water Purity : 99.0% CAS No : N/A Ingredients : BPC157, TB500, GHKCu Poisonous : NO Appearance : Blue powder Taste : Other Smell : Other Product Type : Peptides Application : Pharmaceutical Storage : Freezer Shape : other HS Code : 2937190099