|
LNP delivery system excipient mPEG-DSPE-2K
Product Details:
- Melting Point 53℃ ~ 54℃
- Storage Freezer
- Smell No Smell
- Taste Other
- Molecular Formula C45H87NNaO11P
- Solubility Sparingly soluble in Chloroform and Methanol
- Shelf Life 24 Months
- Click to View more
LNP delivery system excipient mPEG-DSPE-2K Price And Quantity
- 140.00 USD ($)/Gram
- 1 Gram
LNP delivery system excipient mPEG-DSPE-2K Product Specifications
- Other
- DSPE-MPEG2000 is used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.
- Powder
- Not less than 95.0%
- White or off-white solid
- Freezer
- Medicine Grade
- Other
- No Smell
- 53℃ ~ 54℃
- 24 Months
- Sparingly soluble in Chloroform and Methanol
- 3907209090
- 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
- 147867-65-0
- 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
- C45H87NNaO11P
LNP delivery system excipient mPEG-DSPE-2K Trade Information
- Shanghai or Beijing
- 10000 Gram Per Month
- 10 Days
- Yes
- If order is confirmed we will reimburse the sample cost
- 1g/bottle, 5g/bottle or according to the requirements from customers.
- Asia Australia North America Western Europe Middle East Africa Eastern Europe South America Central America
- All India
- ISO
Product Description
MPEG2000-DSPE combines the amphiphilic properties of phospholipids and the hydrophilic polymer properties of PEG. In recent years, its application in drug carriers such as long-circulating liposomes, polymer micelles, and long-circulating nanoparticles has achieved rapid development. According to the management of pharmaceutical excipients in my country, the molecular weight of polyethylene glycol in the MPEG2000-DSPE molecule is about 2000, which is suitable for the preparation of long-circulating liposomes, so that liposomes will not be captured by MPS-rich tissues immediately after intravenous injection. As a result, the circulation time in the blood is prolonged, thereby increasing the chance of entering pathological tissues.
The amount of MPEG2000-DSPE in doxorubicin liposome DOXIL accounted for 20% of the total lipid, and compared with ordinary doxorubicin liposome Mycoet, the kinetic difference was obvious. The plasma half-life of liposomal doxorubicin, DOXIL is 2.5d, while Myocet is only 0.07h.
Other Products in 'Pharmaceutical Excipients' category
DALIAN HANDOM CHEMICALS CO.,LTD.
All Rights Reserved.(Terms of Use) Developed and Managed by Infocom Network Private Limited. |