
LNP delivery system excipient mPEG-DSPE-2K
Product Details:
- Molecular Formula C45H87NNaO11P
- Melting Point 53 ~ 54
- Smell No Smell
- HS Code 3907209090
- Storage Freezer
- Shelf Life 24 Months
- Solubility Sparingly soluble in Chloroform and Methanol
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LNP delivery system excipient mPEG-DSPE-2K Price And Quantity
- 1 Gram
- 140.00 USD ($)/Gram
LNP delivery system excipient mPEG-DSPE-2K Product Specifications
- 53 ~ 54
- Powder
- Other
- 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
- C45H87NNaO11P
- Not less than 95.0%
- Medicine Grade
- Other
- 24 Months
- 147867-65-0
- Sparingly soluble in Chloroform and Methanol
- DSPE-MPEG2000 is used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.
- 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
- No Smell
- White or off-white solid
- 3907209090
- Freezer
LNP delivery system excipient mPEG-DSPE-2K Trade Information
- Shanghai or Beijing
- 10000 Gram Per Month
- 10 Days
- Yes
- If order is confirmed we will reimburse the sample cost
- 1g/bottle, 5g/bottle or according to the requirements from customers.
- Asia Australia North America Western Europe Middle East Africa Eastern Europe South America Central America
- All India
- ISO
Product Description
MPEG2000-DSPE combines the amphiphilic properties of phospholipids and the hydrophilic polymer properties of PEG. In recent years, its application in drug carriers such as long-circulating liposomes, polymer micelles, and long-circulating nanoparticles has achieved rapid development. According to the management of pharmaceutical excipients in my country, the molecular weight of polyethylene glycol in the MPEG2000-DSPE molecule is about 2000, which is suitable for the preparation of long-circulating liposomes, so that liposomes will not be captured by MPS-rich tissues immediately after intravenous injection. As a result, the circulation time in the blood is prolonged, thereby increasing the chance of entering pathological tissues.
The amount of MPEG2000-DSPE in doxorubicin liposome DOXIL accounted for 20% of the total lipid, and compared with ordinary doxorubicin liposome Mycoet, the kinetic difference was obvious. The plasma half-life of liposomal doxorubicin, DOXIL is 2.5d, while Myocet is only 0.07h.

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