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LNP delivery system excipient mPEG-DSPE-2K

LNP delivery system excipient mPEG-DSPE-2K

140.00 USD ($)/Gram

Product Details:

  • Melting Point 53 ~ 54
  • Storage Freezer
  • HS Code 3907209090
  • Shelf Life 24 Months
  • Taste Other
  • Smell No Smell
  • Solubility Sparingly soluble in Chloroform and Methanol
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LNP delivery system excipient mPEG-DSPE-2K Price And Quantity

  • 140.00 USD ($)/Gram
  • 1 Gram

LNP delivery system excipient mPEG-DSPE-2K Product Specifications

  • DSPE-MPEG2000 is used as one of the LNP Delivery System Excipients for mRNA medicines or drugs.
  • Other
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • 53 ~ 54
  • White or off-white solid
  • Freezer
  • 3907209090
  • 24 Months
  • Sparingly soluble in Chloroform and Methanol
  • C45H87NNaO11P
  • Other
  • 147867-65-0
  • Powder
  • No Smell
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • Medicine Grade
  • Not less than 95.0%

LNP delivery system excipient mPEG-DSPE-2K Trade Information

  • Shanghai or Beijing
  • 10000 Gram Per Month
  • 10 Days
  • Yes
  • If order is confirmed we will reimburse the sample cost
  • 1g/bottle, 5g/bottle or according to the requirements from customers.
  • Asia Australia North America Western Europe Middle East Africa Eastern Europe South America Central America
  • All India
  • ISO

Product Description

MPEG2000-DSPE combines the amphiphilic properties of phospholipids and the hydrophilic polymer properties of PEG. In recent years, its application in drug carriers such as long-circulating liposomes, polymer micelles, and long-circulating nanoparticles has achieved rapid development. According to the management of pharmaceutical excipients in my country, the molecular weight of polyethylene glycol in the MPEG2000-DSPE molecule is about 2000, which is suitable for the preparation of long-circulating liposomes, so that liposomes will not be captured by MPS-rich tissues immediately after intravenous injection. As a result, the circulation time in the blood is prolonged, thereby increasing the chance of entering pathological tissues.

The amount of MPEG2000-DSPE in doxorubicin liposome DOXIL accounted for 20% of the total lipid, and compared with ordinary doxorubicin liposome Mycoet, the kinetic difference was obvious. The plasma half-life of liposomal doxorubicin, DOXIL is 2.5d, while Myocet is only 0.07h.

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