Back to top
--+8615840669648
Send Inquiry
DSIP China
DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China
DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China DSIP China

DSIP China

3.5 USD ($)/Piece

Product Details:

  • Properties DSIP peptide ( -sleep-inducing peptide), a classic natural nonapeptide, is unique primarily due to its special structural design, central nervous system hurdle-crossing ability, and unique biological characteristics. We can summarize its core features into the following four aspects: 1. Structural and Physical Characteristics: Small and Extremely Soluble Ultra-small molecular structure: It consists of only 9 amino acids. Compared to the 28 amino acid VIP peptide, DSIP's structure is much simpler, with a molecular weight of only 848.8 g/mol. High water solubility and stability (powder state): As a short peptide, its white lyophilized powder state exhibits excellent water solubility. Its chemical structure is very stable and does not easily denature under a dry, light-protected environment at -20 C. 2. Pharmacokinetic Characteristics: Hurdle-crossing ability and rapid metabolism Excellent blood-brain barrier permeability: This is the most crucial physicobiological characteristic of DSIP. Most peptides, due to their large molecular size, have difficulty entering the brain from the bloodstream. DSIP, however, can cross the blood-brain barrier (BBB) relatively freely, acting directly on the central nervous system, which is a major prerequisite for its precise sleep regulation. Extremely short in vivo lifespan: Similar to VIP peptides, DSIP has a very short half-life in the bloodstream (only a few minutes). After entering the body, it is rapidly broken down and degraded by aminopeptidases in the blood and tissues. 3. Biological characteristics of action: "Smoothing" rather than "forcing" Non-sedative induction: This is its biggest difference from ordinary sleeping pills (such as benzodiazepines). DSIP does not forcibly paralyze nerves, nor does it change the normal sleep structure (e.g., it does not suppress REM sleep). It works by "smoothing" brain waves, inducing the brain to produce slow waves (Delta waves), allowing the body to enter deep sleep in accordance with its natural biological clock. A bidirectional regulator: It not only helps with sleep but also helps maintain wakefulness during the day. It functions more like a "clock regulator," bidirectionally regulating neurotransmitter release based on the body's diurnal environment, exhibiting strong adaptogen characteristics. 4. Powerful "Stress Resistance" and "Drug Resistance" Characteristics HPA Axis Protector: DSIP possesses a powerful "braking" effect when facing acute mental or physical stress. It inhibits the release of corticotropin-releasing factor (CRF) from the hypothalamus, thereby preventing a surge in stress hormones (cortisol). No Tolerance or Addiction: In animal studies, long-term administration of DSIP peptides did not induce dependence (addiction) like with traditional drugs, nor did it trigger rebound insomnia upon discontinuation.
  • Appearance Research Grade
  • Purity 99%
  • HS Code 2937190099
  • Shape other
  • Storage Freezer
  • Physical Form Powder
  • Click to View more
X

DSIP China Price And Quantity

  • 10 Piece
  • 3.5 USD ($)/Piece

DSIP China Product Specifications

  • other
  • Pharmaceutical
  • Peptides
  • Powder
  • Freezer
  • Other
  • Research Grade
  • 1. Sleep Disorders and Slow-Wave Sleep Research (Core Use) This is the most well-known and widely used research application of DSIP peptides. Inducing Deep Slow-Wave Sleep: Researchers use it to stimulate the brain to produce Delta ( ) brain waves. These brain waves can induce a deep sleep stage in humans and laboratory animals, characterized by high cellular repair. Chronic Insomnia Management Research: In some early clinical and small-scale studies, it has been used to explore ways to improve sleep efficiency in patients with chronic severe insomnia, shortening the time required to fall asleep (sleep latency) without altering normal sleep structure. 2. Stress Management and HPA Axis (Hypothalamic-Pituitary-Adrenal Axis) Regulation DSIP acts as a powerful "braking system" in dealing with physical and mental stress. Inhibiting Stress Hormone Surges: In animal models of high stress or anxiety, DSIP has been used to regulate the brain's HPA axis. It inhibits the excessive release of adrenocorticotropic hormone (ACTH) and cortisol (stress hormones), achieving anti-anxiety and mood-stabilizing effects. 3. Chronic Pain Management and Addiction Withdrawal Research (Neuroscience) Relief of Endogenous Pain: DSIP peptides exhibit certain analgesic properties. In neurological studies, scientists investigate how it affects the endorphin system, thereby relieving chronic or neuropathic pain. Alcohol and Drug Withdrawal Management: Some preclinical studies use DSIP to explore how to reduce withdrawal symptoms after dependence on alcohol or certain drugs, helping the nervous system return to stability. 4. Laboratory Basic Science and Anti-aging Research As a high-purity lyophilized powder (such as the commonly available 5mg reagent), its main uses include: Antioxidant and Cell Protection:** As an endogenous antioxidant, it is used to explore the mechanisms by which it scavenges free radicals and protects brain neurons from oxidative stress damage. Exploration of Neurodegenerative Diseases:** Academic institutions and pharmaceutical companies frequently use it to study the neurotoxic protective mechanisms in models of Alzheimer's disease, Parkinson's disease, etc. Electroencephalological studies: By injecting or perfusing this polypeptide, changes in slow wave rhythms in animal electroencephalograms (EEGs) were observed and recorded.
  • NO
  • 62568-57-4
  • C35H48N10O15
  • Research Grade
  • Soluble in water
  • N/A
  • DSIP peptide ( -sleep-inducing peptide), a classic natural nonapeptide, is unique primarily due to its special structural design, central nervous system hurdle-crossing ability, and unique biological characteristics. We can summarize its core features into the following four aspects: 1. Structural and Physical Characteristics: Small and Extremely Soluble Ultra-small molecular structure: It consists of only 9 amino acids. Compared to the 28 amino acid VIP peptide, DSIP's structure is much simpler, with a molecular weight of only 848.8 g/mol. High water solubility and stability (powder state): As a short peptide, its white lyophilized powder state exhibits excellent water solubility. Its chemical structure is very stable and does not easily denature under a dry, light-protected environment at -20 C. 2. Pharmacokinetic Characteristics: Hurdle-crossing ability and rapid metabolism Excellent blood-brain barrier permeability: This is the most crucial physicobiological characteristic of DSIP. Most peptides, due to their large molecular size, have difficulty entering the brain from the bloodstream. DSIP, however, can cross the blood-brain barrier (BBB) relatively freely, acting directly on the central nervous system, which is a major prerequisite for its precise sleep regulation. Extremely short in vivo lifespan: Similar to VIP peptides, DSIP has a very short half-life in the bloodstream (only a few minutes). After entering the body, it is rapidly broken down and degraded by aminopeptidases in the blood and tissues. 3. Biological characteristics of action: "Smoothing" rather than "forcing" Non-sedative induction: This is its biggest difference from ordinary sleeping pills (such as benzodiazepines). DSIP does not forcibly paralyze nerves, nor does it change the normal sleep structure (e.g., it does not suppress REM sleep). It works by "smoothing" brain waves, inducing the brain to produce slow waves (Delta waves), allowing the body to enter deep sleep in accordance with its natural biological clock. A bidirectional regulator: It not only helps with sleep but also helps maintain wakefulness during the day. It functions more like a "clock regulator," bidirectionally regulating neurotransmitter release based on the body's diurnal environment, exhibiting strong adaptogen characteristics. 4. Powerful "Stress Resistance" and "Drug Resistance" Characteristics HPA Axis Protector: DSIP possesses a powerful "braking" effect when facing acute mental or physical stress. It inhibits the release of corticotropin-releasing factor (CRF) from the hypothalamus, thereby preventing a surge in stress hormones (cortisol). No Tolerance or Addiction: In animal studies, long-term administration of DSIP peptides did not induce dependence (addiction) like with traditional drugs, nor did it trigger rebound insomnia upon discontinuation.
  • Other
  • DSIP
  • 99%
  • 24 Months
  • 2937190099

DSIP China Trade Information

  • Shenzhen
  • Telegraphic Transfer (T/T), Western Union
  • 10000 Piece Per Week
  • 3 Days
  • Yes
  • If order is confirmed we will reimburse the sample cost
  • 10 vials/box
  • Asia, Australia, North America, Western Europe
  • GMP, ISO

Product Description

DSIP peptide (Delta Sleep-Inducing Peptide) is a natural small neuropeptide composed of 9 amino acids. It was first isolated from the cerebral blood flow of sleeping rabbits by Swiss scientists in 1977. In the human body, it is mainly found in the brain, pituitary gland, and peripheral organs, and is a very important multifunctional regulatory substance.
Tell us about your requirement
product

Price:

Quantity
Select Unit

  • 50
  • 100
  • 200
  • 250
  • 500
  • 1000+
Additional detail
Mobile number

Email

Other Products in 'Peptide Preparations' category