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IGF-1 LR3 China

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Product Details:

Shelf Life 18 Months
Molecular Weight 9.1 kDa Drams (dr)
Storage Freezer
CAS No 946870-92-4
Ph Level pH value of 6.5 7.5 (in solution)
Usage IGF-1 LR3 (Long-Arg3-Insulin-like Growth Factor-1) is a synthetic peptide derivative with a half-life of approximately 20 to 30 hours. Common Usage and Dosage (Based on non-standardized sources and exploratory clinical data) Administration: Typically administered via subcutaneous (SubQ) injection into areas with thinner subcutaneous fat or good circulation, such as the abdomen or thighs; it can also be administered via intramuscular (IM) injection. Reference Dosage: In online discussions and non-clinical contexts, common micro-doses range from 10 mcg to 50 mcg per day (while some extreme or non-clinical sources may suggest doses exceeding 100 mcg, this carries a very high level of risk). Cycle Duration: It is generally recommended to use the substance for 4 to 6 weeks, followed by a break of at least 4 weeks (or longer) to prevent a decline in receptor sensitivity (receptor desensitization).
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IGF-1 LR3 China Price And Quantity

Minimum Order Quantity 10 Piece
Price 4.0 USD ($)/Piece

IGF-1 LR3 China Product Specifications

Purity Not less than 99.00%
Appearance White powder
Ingredients igf-1 lr3
Taste Odorless
Usage IGF-1 LR3 (Long-Arg3-Insulin-like Growth Factor-1) is a synthetic peptide derivative with a half-life of approximately 20 to 30 hours. Common Usage and Dosage (Based on non-standardized sources and exploratory clinical data) Administration: Typically administered via subcutaneous (SubQ) injection into areas with thinner subcutaneous fat or good circulation, such as the abdomen or thighs; it can also be administered via intramuscular (IM) injection. Reference Dosage: In online discussions and non-clinical contexts, common micro-doses range from 10 mcg to 50 mcg per day (while some extreme or non-clinical sources may suggest doses exceeding 100 mcg, this carries a very high level of risk). Cycle Duration: It is generally recommended to use the substance for 4 to 6 weeks, followed by a break of at least 4 weeks (or longer) to prevent a decline in receptor sensitivity (receptor desensitization).
Physical Form Powder
Product Type Peptides
Ph Level pH value of 6.5 7.5 (in solution)
EINECS No 1592732-453-0
HS Code 2937190099
Properties IGF-1 LR3 (Long R3 Insulin-like Growth Factor-I) is an engineered, recombinant analogue of naturally occurring insulin-like growth factor-1 (IGF-1). Key Structural Characteristics Amino Acid Structure: It features an extension of 13 amino acids at the N-terminus of the native IGF-1 molecule, with the glutamic acid at position 3 replaced by arginine (Arg). It consists of a total of 83 amino acids (with a molecular weight of approximately 9.1 kDa). Reduced Binding Affinity: Due to these structural modifications, its affinity for IGF-binding proteins (IGFBPs) is significantly reduced to only a small percentage (or even less) of that of native IGF-1. Extended Duration of Action: Because it is not rapidly inactivated or cleared by binding proteins, its half-life in the body is substantially prolonged, leading to significantly enhanced biological activity. Primary Biological Properties Receptor Binding: It exhibits high affinity for the IGF-1 receptor (IGF-IR) and potently activates the downstream AKT signaling pathway. Promotion of Growth and Proliferation: It possesses a robust capacity to stimulate cell growth, differentiation, and protein synthesis, while also inhibiting apoptosis (programmed cell death). Tissue and Metabolic Effects: It promotes muscle growth and repair, supports the repair and regeneration of nerve cells, stimulates fibrous tissue proliferation, and contributes to some extent to energy utilization and fat loss. Applications: In scientific research and biotechnology, it is frequently used as a highly effective additive in serum-free cell culture media to facilitate the production of recombinant proteins and enhance cell proliferation.
CAS No 946870-92-4
Storage Freezer
Application Pharmaceutical
Smell Other
Molecular Weight 9.1 kDa Drams (dr)
Molecular Formula C400H625N111O115S9
Shelf Life 18 Months
Poisonous NO
Grade Research Grade
Shape other

IGF-1 LR3 China Trade Information

FOB Port Shenzhen or Guangzhou
Payment Terms Telegraphic Transfer (T/T), Western Union
Supply Ability 10000 Piece Per Week
Delivery Time 5 Days
Sample Available Yes
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Packaging Details 10 Vials per Kit
Main Export Market(s) North America, South America, Western Europe, Asia, Australia
Certifications GMP, ISO9001

Product Description

IGF-1 LR3 (full name: Long R3 Insulin-like Growth Factor-I; a recombinant human long-chain insulin-like growth factor-1) is a synthetically modified analog of naturally occurring insulin-like growth factor-1 (IGF-1).

Basic Structure and Characteristics

Molecular Structure: It consists of 83 amino acidscontaining 13 additional amino acids at the N-terminus compared to natural IGF-1with the glutamic acid at position 3 replaced by arginine.

Long-acting Nature: This structural modification significantly reduces its affinity for insulin-like growth factor-binding proteins (IGFBPs) in the human body. Consequently, its half-life in vivo is extended (typically reaching 2030 hours or longer), and its biological activity is substantially higher than that of natural IGF-1.

Mechanism of Action: It serves as a potent activator of the AKT signaling pathway. By binding to specific receptors (IGF1R) on the cell surface, it promotes cell growth, proliferation, and protein synthesis, while simultaneously inhibiting apoptosis (programmed cell death).

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